Asthma
Overview
Asthma is a chronic inflammatory disease of the airways characterized by reversible airflow obstruction, bronchial hyperresponsiveness, and airway remodeling. It affects approximately 300 million people worldwide.
Classification by Severity
| Step | Severity | Symptoms | Treatment |
|---|---|---|---|
| 1 | Intermittent | ≤2 days/week | SABA PRN |
| 2 | Mild persistent | >2 days/week | Low-dose ICS |
| 3 | Moderate | Daily | Medium ICS + LABA |
| 4 | Severe | Throughout day | High ICS + LABA |
Common Triggers
- Allergens — Dust mites, pollen, pet dander, mold
- Irritants — Smoke, pollution, strong odors
- Infections — Viral upper respiratory infections
- Exercise — Especially in cold, dry air
- Medications — Aspirin, NSAIDs, beta-blockers
Key Management Principles
- Controller medications — Daily anti-inflammatory therapy
- Reliever medications — Quick-relief for acute symptoms
- Trigger avoidance — Environmental control measures
- Action plan — Written plan for self-management
- Regular monitoring — Peak flow, spirometry
Asthma control, not severity, should drive treatment decisions. A well-controlled asthma patient on Step 4 therapy has better outcomes than an uncontrolled patient on Step 2.
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