Hormone Replacement Therapy
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Overview
Hormone Replacement Therapy (HRT) is a medical treatment used to supplement the body with hormones that are no longer produced in sufficient quantities, most commonly estrogen and progesterone during menopause.
Types of HRT
| Type | Hormones | Route | Indication |
|---|---|---|---|
| Combined HRT | Estrogen + Progesterone | Oral/Patch | Women with uterus |
| Estrogen-only | Estrogen | Oral/Patch/Gel | Post-hysterectomy |
| Testosterone | Testosterone | Injection/Gel | Male hypogonadism |
| Bioidentical | Custom blends | Various | Personalized therapy |
Benefits
- Vasomotor symptom relief — Hot flashes and night sweats
- Bone protection — Prevents osteoporosis-related fractures
- Urogenital health — Reduces vaginal dryness and UTI risk
- Mood stabilization — Alleviates anxiety and depression
Monitoring Protocol
- Baseline labs — Hormone panel, lipids, liver function
- Follow-up at 3 months — Symptom assessment and dose adjustment
- Annual review — Risk-benefit reassessment
- Mammography — Annual screening while on therapy
Current evidence supports HRT initiation within 10 years of menopause onset for maximum cardiovascular and bone benefit with minimal risk.
Contraindications
- History of breast cancer
- Active liver disease
- Unexplained vaginal bleeding
- History of blood clots (VTE)
- Active cardiovascular disease
Procedimientos relacionados
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